Multinational, Missouri-based biotechnology company Alden is introducing a suspended simultaneous sandwich assay, a new pathway for ensuring food safety, quality and compliance.
Safeguarding meat and poultry products for consumers is time sensitive, and traditional testing modalities take several days to produce results. Alden recognized the need for a faster, simpler testing method. Alden showcased the company's next-generation diagnostic testing solutions at the Annual Meeting of the International Association for Food Processing, July 14-17, 2024, in Long Beach, Calif.
While polymerase chain reaction testing is currently the most commonly used method for detecting the presence of pathogens like E. coli, Alden has created a novel, bead-based testing method that functions differently. Third-party laboratory studies deem the Alden platform to work "as well as or better" than PCR.
"This test marks a pivotal moment for the food and agriculture supply chain because we've decreased time-to-result from a few days to a few hours – so we're saving our customers time, lowering their costs, improving their operations, and dramatically empowering them to manage and mitigate risk within their operations," said Elijah Sharpe, Alden founder and chief executive officer. "Our testing platform is the first of its kind, and it's the ideal solution for food industry professionals who need to spend less time analyzing results and more time taking action."
The AOAC Research Institute Performance Tested Methods Program recently certified Alden's S1 for E. coli O157 testing method for E. coli O157 (including H7) detection in ground beef (375 g and 25 g) and beef trim (375 g) (PTM #042401). Comparing the SSSA approach to the USDA/FSIS Microbiology Laboratory Guidebook (5C.03) and the ISO Technical Standard 13136:2012 PCR reference methods, the PTM program found "no statistically significant difference from the reference methods."
Those are welcomed results for meat processors and consumers who face the consequences of undetected outbreaks. Several additional microbe tests are on track for PTM validation in the coming months, including Listeria, Salmonella, Campylobacter and others.
Unlike legacy testing systems such as PCR, enzyme-linked immunosorbent assay and lateral flow testing, Alden is safest for use within a production environment because personnel, product and equipment have zero risk of being exposed to potentially harmful control pathogens.
Alden's use of SSSA technology involves a small sample volume being placed into the cuvette containing the SSSA. What follows is a new scientific approach using nanoparticles, proprietary coatings and custom ratios to simultaneously capture and detect targeted bacteria, resulting in a visible change.
Alden's technology is available via off-site laboratory testing and Alden's portable on-site testing solution. Either way, customers have access to an online platform that digitizes results and provides transparency into every step of the testing workflow.
According to Austin Gray, Alden's chief operating officer, the platform empowers businesses to ensure operational continuity, maintain product safety and comply with stringent regulatory standards.
"At Alden, we've made it our mission to support a safer, healthier world by modernizing the way we test for dangerous microbes in the food we eat," said Gray.
Source: Alden
